As a red light therapy wellness specialist, I hear this question almost every day: should you use red light therapy before your skincare or after it? The short answer is that the order can matter, primarily because light needs to reach its target tissues to do its job. The longer answer is more nuanced. In this guide, I’ll explain what red light therapy actually does in skin, what credible research supports, where expert caution is warranted, and how to structure your routine so you get the most out of both your device and your products—without irritating your skin.
What Red Light Therapy Does in Skin
Red light therapy—also called low-level light therapy or photobiomodulation—is a noninvasive approach that uses specific red and near‑infrared wavelengths to stimulate cellular function. Reputable medical sources summarize the mechanism consistently: mitochondria absorb light and raise cellular energy (ATP), which can support collagen synthesis, calm inflammation, and enhance tissue repair. This basic biology has been described by clinical programs at Penn State Behrend and consumer health resources from Cleveland Clinic, and it aligns with decades of lab and clinical exploration.
It is important to distinguish red light therapy from photodynamic therapy. Photodynamic therapy uses a photosensitizing drug plus targeted light to destroy abnormal cells and is used in dermatology for certain conditions. Red light therapy, in contrast, does not destroy tissue; it aims to promote repair and reduce inflammation. Stanford Medicine emphasizes this difference and notes that dermatology’s strongest evidence for red light therapy remains in hair regrowth and modest wrinkle reduction, with other claims still developing.
A controlled clinical trial indexed on PubMed Central tested full‑body red light in the 611–650 nm range twice weekly across 30 sessions and found improvements in subjective skin feel and appearance, measured reductions in skin roughness, and increased intradermal collagen density. That same trial found no advantage for adding broader spectra compared with red‑only in those settings, which suggests getting the dose right may be more important than stacking many colors. Consumer health summaries from Cleveland Clinic, UCLA Health, and Harvard Health converge on a practical view: for skin and hair, results are incremental, typically require repeated sessions, and remain safest when you protect your eyes and avoid overuse.
Why the Order Question Comes Up
Light must reach living cells to do its job. Anything you layer on top of your skin can, in theory, reflect, scatter, or absorb some portion of that light before it penetrates. That is the core reason many in-office protocols—and the clinical trial I referenced—apply red light to clean, product‑free skin. At the same time, several dermatology clinics and device makers note that gentle hydrating products can be used around sessions for comfort and potential synergy, especially when a device requires a conductive or hydrating medium.
Here is what the published sources do and do not tell us. There are no head‑to‑head clinical trials that directly compare “red light before products” versus “red light after products” on real‑world home routines. What we do have are credible mechanisms, consistent device safety guidance, and trials showing benefit when the skin is not covered with occlusive layers. So the sequencing decision is mostly practical: maximize light reaching your targets while keeping your skincare well tolerated.

The Case for Red Light Before Skincare
In my practical experience guiding at‑home users and collaborating with dermatology clinics, using red light on clean, dry skin is the most reliable default. You remove barriers, minimize optical scatter, and mirror how much of the medical literature and in‑clinic protocols deliver light. If you are chasing collagen support, fine line softening, or post‑procedure calming, the clean‑skin approach streamlines setup and reduces the chance that an active product will interact with the light session to cause irritation.
For a morning routine, many people do their red light session on clean skin, then apply a hydrating serum, moisturizer, and sunscreen for the day. For an evening routine, a clean‑skin session followed by your regular moisturizer is straightforward and comfortable. If you use prescription or over‑the‑counter actives like retinoids, benzoyl peroxide, or strong acids, spacing them away from the session can reduce the chance of irritation; device makers often advise avoiding those specific actives during a light session itself. That is a practical, skin‑kind choice rather than a claim that they are unsafe with light.

When Red Light After Skincare Makes Sense
There are real‑world scenarios where you may choose to use products before the session. Some masks and wands are designed to glide over a thin, water‑based conductive or hydrating gel. Some clinics also layer gentle hydrating serums or masks and then illuminate, with the goal of comfort and potential synergy. Dermatology clinics that offer facials, peels, or microneedling commonly finish those services with red light to help calm redness and support early repair, and that post‑procedure sequence is sensible.
If you take the “products first” path at home, keep the layers light and non‑occlusive. Water‑based, fragrance‑free hydrating serums that do not contain exfoliating acids, benzoyl peroxide, or retinoids are the safer pairings from a skin‑comfort standpoint. Heavy creams, thick mineral pigments, or balms can behave like optical barriers and may make your session less efficient. That is not a safety hazard; it is just not the most efficient use of your time under the light.
How I Decide the Order With Clients
I start from the goal, then pick the order that minimizes barriers and irritation. For a user targeting fine lines and firmness, I favor light first on clean skin, then skincare. For post‑treatment calming after a peel or microneedling, applying light at the end of the service is a well‑established in‑office sequence and translates well to home use when your skin is clean. For acne‑prone skin, red light can help with inflammation and healing; if you also use benzoyl peroxide or retinoids, separate them from the light session to avoid stacking irritation. For sensitive or redness‑prone skin, stick with clean skin under the light and keep post‑session products gentle and fragrance‑free.
I also match the time of day to the person. Some users report feeling pleasantly energized after sessions, while others find it relaxing. That subjective response is normal and even surfaced in clinician discussions published by University of Utah Health. There is no compelling evidence that morning or evening is biologically superior; choose the time you can keep consistently.
Device and Dosing Basics You Can Trust
While this article focuses on order, dose matters more than almost anything else. The dermatology literature most often references red wavelengths in the 600s and near‑infrared wavelengths roughly in the 800s, with specific device choices tuned to the target tissue depth. The PubMed Central controlled trial demonstrating skin improvements used red in the 611–650 nm range. Stanford Medicine emphasizes that outcomes depend on wavelength, dose, duration, and frequency, and that at‑home tools are typically less powerful than clinical systems, which explains why clinics often deliver faster results.
Consumer‑facing education from Cleveland Clinic and hospital systems like UCLA Health and UPMC describe typical at‑home sessions as brief and repeated: about 10–20 minutes per area, several times per week, with consistency over weeks to months. Safety guidance across Harvard Health, Cleveland Clinic, and UCLA Health is consistent: red light therapy does not use UV, appears low risk when used as directed, and warrants eye protection and adherence to device instructions. FDA clearance on consumer devices signals that a device meets safety requirements; it is not a guarantee of effectiveness. The American Academy of Dermatology cautions that darker skin can be more sensitive to visible light, which can increase the risk of longer‑lasting dark spots if irritation or overexposure occurs, so start low and consult a dermatologist if you have a history of hyperpigmentation.

Before vs After: Practical Comparison
Decision Factor |
Red Light Before Products |
Red Light After Products |
Light reaching targets |
Maximizes penetration by minimizing barriers on skin |
Acceptable with a thin, water‑based gel or serum; thick creams can reduce efficiency |
Irritation risk with actives |
Lower, because actives are applied after the session |
Higher if acids, retinoids, or benzoyl peroxide are layered first; best to avoid during session |
Post‑procedure pairing |
Common in clinics to light clean skin post‑peel or post‑microneedling |
Also common immediately after professional treatments when skin is clean and product‑free |
Comfort and feel |
Simple and quick; add soothing skincare after |
Comfortable when paired with gentle hydrating gels; avoid fragranced or essential‑oil‑heavy products |
Daytime routines |
Do session on clean skin, then apply moisturizer and sunscreen |
If you prefer products first, keep them light; always apply sunscreen after the session |
Consistency and habit |
Easy to standardize; mirrors research protocols |
Works well if your device was designed to glide over a hydrating medium |
Sample Routines You Can Copy
For a morning anti‑aging routine, cleanse, do your red light session on clean, dry skin, then apply a hydrating serum and your moisturizer, and finish with sunscreen before you head out. For an evening recovery routine, cleanse, use red light on clean skin, and then apply a soothing moisturizer. If your device requires a glide medium, use a thin, fragrance‑free, water‑based gel during the session, then rinse lightly or follow with your usual hydrating serum and moisturizer. If you use retinoids, place them on alternate nights or at least separate them from your light session so you do not stack potential irritation.
For acne‑prone skin, the literature distinguishes red light therapy from blue light and from photodynamic therapy. Red light does not destroy oil glands or bacteria; it helps calm inflammation and support healing, and some programs combine red and blue for better outcomes. If your acne routine includes benzoyl peroxide or strong exfoliating acids, give your skin a break during the light session and apply those products later in the day or on alternating days. This keeps your barrier happier without compromising your acne care.
For sensitive or redness‑prone skin, start with shorter sessions and lower frequencies. Keep the skin under your device clean, avoid fragranced products around your session, and apply a gentle moisturizer after. If you have a deeper skin tone and a history of hyperpigmentation, the American Academy of Dermatology’s caution about visible light sensitivity is your cue to start low, go slow, and consider checking in with a board‑certified dermatologist before ramping up.

Safety, Comfort, and Real‑World Results
The safety profile for properly used red light devices is reassuring across Cleveland Clinic, Harvard Health, and UCLA Health. The therapy does not use UV, burns are uncommon and usually associated with device malfunction or misuse, and eye protection remains a must. At‑home devices are intentionally lower power than in‑clinic panels or beds, so expect incremental changes that build with consistency rather than overnight transformations. If you are evaluating a device, look for a reputable manufacturer, clear labeling, and, ideally, FDA clearance for safety.
One more evidence nuance matters for expectations. Stanford Medicine underscores that hair regrowth and wrinkle reduction are where the science is most mature, while claims around athletic performance or sleep are still being worked out. On the aesthetics side, the PubMed Central controlled trial supports improvement in skin feel and collagen density with red wavelengths alone. That tells us you do not need a rainbow of lights to see benefits, but you do need regular, correctly dosed sessions.
So… Does the Order Truly Matter?
Order is not everything, but it is not nothing. If you want the simplest, most evidence‑aligned routine, use red light on clean, dry skin, then apply your skincare. That mirrors how clinical trials and many in‑office protocols deliver light and minimizes barriers between your device and your cells. If your device requires a conductive gel, or you simply prefer the feel of a hydrating serum during use, keep it thin and water‑based, skip acids, retinoids, and benzoyl peroxide around the session, and apply richer products after.
What matters most in the real world is steady use, sensible dosing, excellent eye safety, and skin‑kind product choices. Timing the session before or after your skincare becomes a tool you adjust to your device, your goals, and your skin’s tolerance, not a rigid rule.
Quick Evidence Touchpoints
Penn State Behrend and Cleveland Clinic describe red light therapy as noninvasive photobiomodulation that boosts mitochondrial energy and supports collagen and repair. Stanford Medicine notes the strongest dermatology evidence for hair regrowth and wrinkle reduction and reminds us that dose and device characteristics drive results. A controlled trial archived on PubMed Central found that red‑only wavelengths improved skin texture and intradermal collagen, with no advantage from broader spectra. Harvard Health, UCLA Health, and the American Academy of Dermatology emphasize safety basics: protect your eyes, recognize that home devices are often less powerful than clinic devices, understand that FDA clearance focuses on safety rather than guaranteed efficacy, and go especially slowly if you have darker skin or a history of hyperpigmentation.
FAQ
Can I use sunscreen during a red light session? For practicality, do your red light session on clean skin and apply sunscreen afterward if it is daytime. This approach reduces barriers between the light and your skin and preserves your daytime protection.
Is it okay to pair red light with serums? Yes, if the serum is thin, water‑based, and gentle. Skip exfoliating acids, benzoyl peroxide, and retinoids during the session to reduce irritation risk. Apply those actives later or on alternate days.
Do I need eye protection with at‑home devices? Yes. Major medical sources, including Harvard Health and Cleveland Clinic, advise protecting your eyes and never staring directly into the LEDs or lasers. Follow your device’s instructions for shields or goggles.
How long until I see results? Consumer health guidance from UCLA Health and Cleveland Clinic aligns on this point: results are incremental and require consistent sessions over weeks to months. At‑home routines often use brief sessions several times per week. Clinics may deliver faster changes with higher‑power devices.
Closing thought: If you keep your session on clean skin, protect your eyes, and keep your products gentle around the light, you will capture the core benefits red light therapy can offer—steadily, safely, and with your skin’s long‑term health in mind.
References
- https://lms-dev.api.berkeley.edu/studies-on-red-light-therapy
- https://www.health.harvard.edu/diseases-and-conditions/led-lights-are-they-a-cure-for-your-skin-woes
- https://thewell.northwell.edu/skin-health/red-light-therapy-skincare
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3926176/
- https://blogs.bcm.edu/2025/06/24/led-light-therapy-how-does-it-work-on-your-skin/
- https://behrend.psu.edu/student-life/student-services/counseling-center/services-for-students/wellness-offerings/red-light-therapy
- https://med.stanford.edu/news/insights/2025/02/red-light-therapy-skin-hair-medical-clinics.html
- https://healthcare.utah.edu/the-scope/mens-health/all/2024/06/176-red-light-therapy-just-fad
- https://my.clevelandclinic.org/health/articles/22114-red-light-therapy
- https://www.gundersenhealth.org/health-wellness/aging-well/exploring-the-benefits-of-red-light-therapy


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